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Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases

Terminal RNA uridylyltransferases (TUTases) catalyze template-independent UMP addition to the 3′ hydroxyl of RNA. TUTases belong to the DNA polymerase β superfamily of nucleotidyltransferases that share a conserved catalytic domain bearing three metal-binding carboxylate residues. We have previously...

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Detalhes bibliográficos
Main Authors: Stagno, Jason, Aphasizheva, Inna, Aphasizhev, Ruslan, Luecke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976215/
https://ncbi.nlm.nih.gov/pubmed/17785418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704259104
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