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High-throughput Detection of Human Papillomavirus-18 L1 Gene Methylation, a Candidate Biomarker for the Progression of Cervical Neoplasia
The L1 gene of human papillomavirus-18 (HPV-18) is consistently hypermethylated in cervical carcinomas, but frequently hypo- or unmethylated in exfoliated cells from asymptomatic patients. In precancerous lesions, L1 is sporadically hypermethylated, correlating with the severity of the neoplasia. In...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1975683/ https://ncbi.nlm.nih.gov/pubmed/17175003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.11.010 |
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