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Comparative Genomics of Bordetella pertussis Reveals Progressive Gene Loss in Finnish Strains

BACKGROUND: Bordetella pertussis is a Gram-negative bacterium that infects the human respiratory tract and causes pertussis or whooping cough. The disease has resurged in many countries including Finland where the whole-cell pertussis vaccine has been used for more than 50 years. Antigenic divergenc...

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Detalhes bibliográficos
Main Authors: Heikkinen, Eriikka, Kallonen, Teemu, Saarinen, Lilli, Sara, Rolf, King, Audrey J., Mooi, Frits R., Soini, Juhani T., Mertsola, Jussi, He, Qiushui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975675/
https://ncbi.nlm.nih.gov/pubmed/17878939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000904
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