Microfluidic Platform for Single Nucleotide Polymorphism Genotyping of the Thiopurine S-Methyltransferase Gene to Evaluate Risk for Adverse Drug Events

Prospective clinical pharmacogenetic testing of the thiopurine S-methyltransferase gene remains to be realized despite the large body of evidence demonstrating clinical benefit for the patient and cost effectiveness for health care systems. We describe an entirely microchip-based method to genotype...

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Detalhes bibliográficos
Main Authors: Chowdhury, Jeeshan, Kagiala, Govind V., Pushpakom, Sudeep, Lauzon, Jana, Makin, Alistair, Atrazhev, Alexey, Stickel, Alex, Newman, William G., Backhouse, Christopher J., Pilarski, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975104/
https://ncbi.nlm.nih.gov/pubmed/17690215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.070014
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