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TREM-1–expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases

Triggering receptor expressed on myeloid cells–1 (TREM-1) potently amplifies acute inflammatory responses by enhancing degranulation and secretion of proinflammatory mediators. Here we demonstrate that TREM-1 is also crucially involved in chronic inflammatory bowel diseases (IBD). Myeloid cells of t...

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Hlavní autoři: Schenk, Mirjam, Bouchon, Axel, Seibold, Frank, Mueller, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974863/
https://ncbi.nlm.nih.gov/pubmed/17853946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30602
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