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Pathological pattern of Mdx mice diaphragm correlates with gradual expression of the short utrophin isoform Up71

Utrophin gene is transcribed in a large mRNA of 13 kb that codes for a protein of 395 kDa. It shows amino acid identity with dystrophin of up to 73% and is widely expressed in muscle and non-muscle tissues. Up71 is a short utrophin product of the utrophin gene with the same cysteine-rich and C-termi...

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Autores principales: Hnia, Karim, Tuffery-Giraud, Sylvie, Vermaelen, Marianne, Hugon, Gerald, Chazalette, Delphine, Masmoudi, Ahmed, Rivier, François, Mornet, Dominique
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Pub. Co. 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1974843/
https://ncbi.nlm.nih.gov/pubmed/16457992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2005.11.006
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