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κ-Opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration

Our study examined ethanol self-administration and accumbal dopamine concentration during κ-opioid receptor (KOPr) blockade. Long-Evans rats were trained to respond for 20 min of access to 10% ethanol (with sucrose) over 7 days. Rats were injected s.c. with the long-acting KOPr antagonist, nor-binal...

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Main Authors: Doyon, William M., Howard, Elaina C., Shippenberg, Toni S., Gonzales, Rueben A.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1973091/
https://ncbi.nlm.nih.gov/pubmed/16781738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2006.04.005
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