A spontaneous point mutation in the single 23S rRNA gene of the thermophilic arachaeon Sulfolobus acidocaldarius confers multiple drug resistance.

Development of transformable vectors for thermophilic archaea requires the characterization of appropriate selectable marker genes. Many antibiotic inhibitors of protein biosynthesis are known to bind to rRNA; therefore, we screened 14 for their capacity to inhibit growth of the thermophilic archaeo...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Aagaard, C, Phan, H, Trevisanato, S, Garrett, R A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC197236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8002603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.24.7744-7747.1994
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!