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Pharmacokinetics and cytotoxicity of RSU-1069 in subcutaneous 9L tumours under oxic and hypoxic conditions.

The acute toxicity, pharmacokinetics and hypoxic cytotoxicity of RSU-1069 were investigated using the subcutaneous (sc) rat 9L tumour model. The pharmacokinetics were studied after i.p. injection of RSU-1069 (20 mg kg-1 or 100 mg kg-1). For both doses, the elimination of RSU-1069 followed first-orde...

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Hlavní autoři: Wong, K. H., Koch, C. J., Wallen, C. A., Wheeler, K. T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1972348/
https://ncbi.nlm.nih.gov/pubmed/2021530
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