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Critical factors for the reversal of methotrexate cytotoxicity by folinic acid.

The cytotoxicity of methotrexate (MTX) on representative human tumour cell lines (two cell lines from head and neck carcinomas, two from breast carcinomas, two from osteosarcomas and one lymphoblastoid cell line) was evaluated to: (1) examine the optimal time interval between MTX and folinic acid (F...

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Autori principali: Bernard, S., Etienne, M. C., Fischel, J. L., Formento, P., Milano, G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1991
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971778/
https://ncbi.nlm.nih.gov/pubmed/1997110
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