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Lack of MHC class I antigens and tumour aggressiveness of the squamous cell carcinoma of the larynx.

A series of 60 primary laryngeal and hypopharyngeal tumours, 24 lymph node metastases and normal tissue were evaluated in frozen sections for the expression of MHC class I antigens, using monoclonal antibodies and the APAAP technique. We found 13 tumours presenting total HLA-ABC loss, five with sele...

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Autors principals: Esteban, F., Concha, A., Delgado, M., Pérez-Ayala, M., Ruiz-Cabello, F., Garrido, F.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971557/
https://ncbi.nlm.nih.gov/pubmed/2257212
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