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Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. In vitro and in vivo studies of a drug-lipoprotein complex.

Previous studies have shown that human leukaemic cells and certain tumour tissues have a higher receptor-mediated uptake of low density lipoprotein (LDL) than the corresponding normal cells or tissues. LDL has therefore been proposed as a carrier for anti-cancer agents. In the current study, a water...

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Main Authors: Vitols, S., Söderberg-Reid, K., Masquelier, M., Sjöström, B., Peterson, C.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971505/
https://ncbi.nlm.nih.gov/pubmed/2245164
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