p53 gene mRNA expression and chromosome 17p allele loss in breast cancer.

p53 messenger RNA expression was examined using a cDNA probe in 76 fresh primary breast tumour specimens, 15 of which came from patients treated with toxoxifen prior to surgery. A 2.8 kb mRNA for p53 was expressed in 43 of the 76 specimens. In 19 tumours the levels were similar to those seen in non-...

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Bibliographic Details
Main Authors: Thompson, A. M., Steel, C. M., Chetty, U., Hawkins, R. A., Miller, W. R., Carter, D. C., Forrest, A. P., Evans, H. J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971309/
https://ncbi.nlm.nih.gov/pubmed/2137009
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