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Orthologous Transcription Factors in Bacteria Have Different Functions and Regulate Different Genes

Transcription factors (TFs) form large paralogous gene families and have complex evolutionary histories. Here, we ask whether putative orthologs of TFs, from bidirectional best BLAST hits (BBHs), are evolutionary orthologs with conserved functions. We show that BBHs of TFs from distantly related bac...

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Detalhes bibliográficos
Main Authors: Price, Morgan N, Dehal, Paramvir S, Arkin, Adam P
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971122/
https://ncbi.nlm.nih.gov/pubmed/17845071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030175
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