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Adaptive Evolution of Conserved Noncoding Elements in Mammals

Conserved noncoding elements (CNCs) are an abundant feature of vertebrate genomes. Some CNCs have been shown to act as cis-regulatory modules, but the function of most CNCs remains unclear. To study the evolution of CNCs, we have developed a statistical method called the “shared rates test” to ident...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Su Yeon, Pritchard, Jonathan K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971121/
https://ncbi.nlm.nih.gov/pubmed/17845075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030147
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