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Two classes of extragenic suppressor mutations identify functionally distinct regions of the GroEL chaperone of Escherichia coli.

The GroES and GroEL proteins of Escherichia coli function together as the GroE molecular chaperone machine to (i) prevent denaturation and aggregation and (ii) assist the folding and oligomerization of other proteins without being part of the final structure. Previous genetic and biochemical analyse...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Zeilstra-Ryalls, J, Fayet, O, Georgopoulos, C
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC197010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7961406/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.21.6558-6565.1994
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