Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas.

In this study we have screened a series of 29 primary leiomyosarcomas for abnormalities of both the p53 gene and the MDM2 gene, which encodes a p53-associated protein. SSCP (single-strand conformation polymorphism) analysis and direct sequencing of polymerase chain reaction (PCR)-amplified DNA were...

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Bibliografische gegevens
Hoofdauteurs: Patterson, H., Gill, S., Fisher, C., Law, M. G., Jayatilake, H., Fletcher, C. D., Thomas, M., Grimer, R., Gusterson, B. A., Cooper, C. S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1994
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1969417/
https://ncbi.nlm.nih.gov/pubmed/8198970
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