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CGP 55398, a liposomal Ge(IV) phthalocyanine bearing two axially ligated cholesterol moieties: a new potential agent for photodynamic therapy of tumours.

Ge(IV) phthalocyanine (GePc) with two axially ligated cholesterol moieties was prepared by chemical synthesis and incorporated in a monomeric state into small unilamellar liposomes (CGP 55398). Upon photoexcitation with light wavelengths around its intense absorption peak at 680 nm, GePc shows an ef...

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Autors principals: Segalla, A., Milanesi, C., Jori, G., Capraro, H. G., Isele, U., Schieweck, K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968893/
https://ncbi.nlm.nih.gov/pubmed/8180009
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