The anti-tumour activity of ifosfamide on heterotransplanted testicular cancer cell lines remains unaltered by the uroprotector mesna.

Ifosfamide is clinically used in combination chemotherapy regimens for the treatment of patients with high-grade lymphomas, sarcomas and metastatic germ cell tumours. In order to reduce the oxazophosphorine-related urothelial toxicity, sodium mercaptoethane sulphonate (mesna) is used in different sc...

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Bibliographic Details
Main Authors: Bokemeyer, C., Schmoll, H. J., Ludwig, E., Harstrick, A., Dunn, T., Casper, J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968886/
https://ncbi.nlm.nih.gov/pubmed/8180015
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