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Effects of the ACTH(4-9) analogue, ORG 2766, on vincristine cytotoxicity in two human lymphoma cell lines, U937 and U715.

The use of cytotoxic drug vincristine (VCR) is limited by the occurrence of peripheral neuropathy. A neurotrophic ACTH(4-9) analogue, ORG 2766, is being studied for its protective effect. Possible modulatory effects of ORG 2766 on tumour cell growth and interference with the cytotoxic efficacy of VC...

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Detalhes bibliográficos
Main Authors: Kiburg, B., van de Loosdrecht, A. A., Schweitzer, K. M., Ossenkoppele, G. J., Müller, L. J., Heimans, J. J., Huijgens, P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968834/
https://ncbi.nlm.nih.gov/pubmed/8123480
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