Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter

Different components of the AP1 transcription factor complex appear to have distinct effects on cell proliferation and transformation. In contrast to other AP1 components, JunD has been shown to inhibit cell proliferation. Also, in prior studies, JunD alone bound menin, product of the MEN1 tumor sup...

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Autori principali: Agarwal, Sunita K., Novotny, Elizabeth A., Crabtree, Judy S., Weitzman, Jonathan B., Yaniv, Moshe, Burns, A. Lee, Chandrasekharappa, Settara C., Collins, Francis S., Spiegel, Allen M., Marx, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC196878/
https://ncbi.nlm.nih.gov/pubmed/12960363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834524100
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