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In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy.

The effect of administering the thiol modulating agent buthionine sulfoximine (BSO) in conjunction with alkylating chemotherapy was investigated in vivo in the mouse KHT sarcomas and bone marrow stem cells. Tumour response to treatment was assessed by an in vivo to in vitro excision assay and bone m...

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Bibliografische gegevens
Hoofdauteurs: Siemann, D. W., Beyers, K. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968664/
https://ncbi.nlm.nih.gov/pubmed/8260357
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