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cDNA transfection followed by the isolation of a MCF-7 breast cell line resistant to tamoxifen in vitro and in vivo.

A tamoxifen resistant cell line (clone 9) has been isolated from the tamoxifen sensitive, hormone responsive MCF-7 breast carcinoma cell line after transfection with mixed cDNA libraries, followed by tamoxifen selection in the presence of oestrogens. Transfection was confirmed by Southern analysis w...

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Hlavní autoři: Toi, M., Harris, A. L., Bicknell, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968663/
https://ncbi.nlm.nih.gov/pubmed/8260359
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