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The first external loop of the metal ion transporter DCT1 is involved in metal ion binding and specificity
The yeast null mutant smf1Δ cannot grow on medium containing EGTA. Expression of Smf1p or the mammalian transporter DCT1 (Slc11a2) suppresses the above-mentioned phenotype. Both can also be expressed in Xenopus oocytes, and the uptake activity and their electrophysiological properties can be studied...
Gorde:
Egile Nagusiak: | , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
National Academy of Sciences
2003
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196866/ https://ncbi.nlm.nih.gov/pubmed/12954986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1934572100 |
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