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The first external loop of the metal ion transporter DCT1 is involved in metal ion binding and specificity

The yeast null mutant smf1Δ cannot grow on medium containing EGTA. Expression of Smf1p or the mammalian transporter DCT1 (Slc11a2) suppresses the above-mentioned phenotype. Both can also be expressed in Xenopus oocytes, and the uptake activity and their electrophysiological properties can be studied...

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Detalhes bibliográficos
Main Authors: Cohen, Adiel, Nevo, Yaniv, Nelson, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196866/
https://ncbi.nlm.nih.gov/pubmed/12954986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1934572100
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