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Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability.

Oncogenes and oncosuppressors can deregulate cell replication in tumours, and recently have been shown to influence the probability of apoptosis. The effects of human c-myc and mutated (T24) Ha-ras oncogenes on susceptibility to apoptosis were investigated by introducing them into immortalised rat f...

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Main Authors: Arends, M. J., McGregor, A. H., Toft, N. J., Brown, E. J., Wyllie, A. H.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968632/
https://ncbi.nlm.nih.gov/pubmed/8260364
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