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Tumourigenesis associated with the p53 tumour suppressor gene.

The p53 gene is contained within 16-20 kb of cellular DNA located on the short arm of human chromosome 17 at position 17p13.1. This gene encodes a 393-amino-acid nuclear phosphoprotein involved in the regulation of cell proliferation. Current evidence suggests that loss of normal p53 function is ass...

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Autors principals: Chang, F., Syrjänen, S., Tervahauta, A., Syrjänen, K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968607/
https://ncbi.nlm.nih.gov/pubmed/8398688
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