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A tale of two TUTases

The insertion and deletion of U residues at specific sites in mRNAs in trypanosome mitochondria is thought to involve 3′ terminal uridylyl transferase (TUTase) activity. TUTase activity is also required to create the nonencoded 3′ oligo[U] tails of the transacting guide RNAs (gRNAs). We have describ...

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Bibliographic Details
Main Authors: Aphasizhev, Ruslan, Aphasizheva, Inna, Simpson, Larry
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC196853/
https://ncbi.nlm.nih.gov/pubmed/12954983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1833120100
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