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Cathepsin D in breast secretions from women with breast cancer.

A proteinase accumulated in breast secretions from women with breast cancer has been characterised. Inhibition of the proteolytic activity of breast secretions by pepstatin A showed that the main enzyme involved was an aspartyl proteinase. Determination of its cleavage specificity by SDS-PAGE and am...

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Autors principals: Sánchez, L. M., Ferrando, A. A., Diez-Itza, I., Vizoso, F., Ruibal, A., López-Otin, C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968431/
https://ncbi.nlm.nih.gov/pubmed/8494701
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