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Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae.

Targeted inactivation of the valine (branched-chain amino acid) dehydrogenase gene (vdh) was used to study the role of valine catabolism in the production of tylosin in Streptomyces fradiae and spiramycin in Streptomyces ambofaciens. The deduced products of the vdh genes, cloned and sequenced from S...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Principais autores: Tang, L, Zhang, Y X, Hutchinson, C R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7928973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.19.6107-6119.1994
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