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Regulation of cytochrome P450 gene expression in human colon and breast tumour xenografts.

It is extremely difficult to identify the factors which regulate the expression of drug-metabolising enzymes in man. To address this problem, we have developed a model involving the use of human tumours grown as xenografts in immune deficient mice. Mice bearing human colon or breast tumours as xenog...

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Détails bibliographiques
Auteurs principaux: Smith, G., Harrison, D. J., East, N., Rae, F., Wolf, H., Wolf, C. R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968301/
https://ncbi.nlm.nih.gov/pubmed/8318421
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