Saturation of tumour cell surface receptors for urokinase-type plasminogen activator by amino-terminal fragment and subsequent effect on reconstituted basement membranes invasion.

Single-chain urokinase-type plasminogen activator (pro-uPA) is bound to a specific surface receptor on ovarian cancer HOC-I cells that is incompletely saturated. Saturation of uncovered receptors by uPA polypeptides with intact amino-terminal fragment (ATF) derived from pro-uPA by limited proteolysi...

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Autori principali: Kobayashi, H., Ohi, H., Shinohara, H., Sugimura, M., Fujii, T., Terao, T., Schmitt, M., Goretzki, L., Chucholowski, N., Jänicke, F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1993
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968269/
https://ncbi.nlm.nih.gov/pubmed/8382511
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