Genetic transformation of the Lyme disease agent Borrelia burgdorferi with coumarin-resistant gyrB.

No useful method to genetically manipulate Borrelia burgdorferi, the causative agent of Lyme disease, has been developed previously. We have used resistance to the coumarin antibiotic coumermycin A1, an inhibitor of DNA gyrase, as a genetic marker to monitor the transformation of B. burgdorferi by e...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Samuels, D S, Mach, K E, Garon, C F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196823/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7928965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.19.6045-6049.1994
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