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pH dependent cytotoxicity of N-dodecylimidazole: a compound that acquires detergent properties under acidic conditions.

N-dodecylimidazole is a compound which acquires detergent properties under acidic conditions and might be useful in killing selectively cells in those regions of solid tumours which have a reduced extracellular pH (pHe). We have therefore studied the effects of N-dodecylimidazole against malignant c...

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Detalhes bibliográficos
Main Authors: Boyer, M. J., Horn, I., Firestone, R. A., Steele-Norwood, D., Tannock, I. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968209/
https://ncbi.nlm.nih.gov/pubmed/8427783
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