Regulation of initial vinblastine influx by P-glycoprotein.

P-glycoprotein (PGP) is an energy-dependent efflux pump that serves to protect cells against the cytotoxicity of many natural product drugs including vinblastine (VBL). In this study we investigated the role of PGP in regulating initial VBL influx. The apparent influx of VBL, measured over the first...

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Autores principales: Shalinsky, D. R., Jekunen, A. P., Alcaraz, J. E., Christen, R. D., Kim, S., Khatibi, S., Howell, S. B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1993
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968208/
https://ncbi.nlm.nih.gov/pubmed/8094005
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