Mutations in the -10 TATAAT sequence of the gyrA promoter affect both promoter strength and sensitivity to DNA supercoiling.

Transcription of the gyrA and gyrB genes, which encode the subunits of DNA gyrase, increases in response to DNA relaxation. Previous studies have shown that a small segment of DNA extending from the -10 consensus hexamer to the start of transcription encodes the sequence determinants for this respon...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Straney, R, Krah, R, Menzel, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7523360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.19.5999-6006.1994
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