Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo.

Nikkomycin Z inhibits chitin synthase in vitro but does not exhibit antifungal activity against many pathogens. Assays of chitin synthase isozymes and growth assays with isozyme mutants were used to demonstrate that nikkomycin Z is a selective inhibitor of chitin synthase 3. The resistance of chitin...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	J Bacteriol
Prif Awduron:	Gaughran, J P, Lai, M H, Kirsch, D R, Silverman, S J
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1994
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.18.5857-5860.1994
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