A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.

A novel, potent, semisynthetic pneumocandin, L-733,560, was used to isolate a resistant mutant in Saccharomyces cerevisiae. This compound, like other pneumocandins and echinocandins, inhibits 1,3-beta-D-glucan synthase from Candida albicans (F.A. Bouffard, R.A. Zambias, J. F. Dropinski, J.M. Balkove...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Douglas, C M, Marrinan, J A, Li, W, Kurtz, M B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.18.5686-5696.1994
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