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PrlA and PrlG suppressors reduce the requirement for signal sequence recognition.

Selection for suppressors of defects in the signal sequence of secretory proteins has led most commonly to identification of prlA alleles and less often to identification of prlG alleles. These genes, secY/prlA and secE/prlG, encode integral membrane components of the protein translocation system of...

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Published in:J Bacteriol
Main Authors: Flower, A M, Doebele, R C, Silhavy, T J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.18.5607-5614.1994
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