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Molecular Evolution of the Rab-Escort-Protein/Guanine-Nucleotide-Dissociation-Inhibitor Superfamily

Prenylation of Rab GTPases regulating vesicle traffic by Rab geranylgeranyltransferase (RabGGTase) requires a complex formed by the association of newly synthesized Rab proteins with Rab-escort-protein (REP), the choroideremia-gene-product that is mutated in disease, leading to loss of vision. After...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alory, Christelle, Balch, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196578/
https://ncbi.nlm.nih.gov/pubmed/12972569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-04-0227
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