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IGF binding protein-3 regulates hematopoietic stem cell and endothelial precursor cell function during vascular development

We asked whether the hypoxia-regulated factor, insulin-like growth factor binding protein-3 (IGFBP3), could modulate stem cell factor receptor (c-kit(+)), stem cell antigen-1 (sca-1(+)), hematopoietic stem cell (HSC), or CD34(+) endothelial precursor cell (EPC) function. Exposure of CD34(+) EPCs to...

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Detalhes bibliográficos
Main Authors: Chang, Kyung-Hee, Chan-Ling, Tailoi, McFarland, Evan L., Afzal, Aqeela, Pan, Hao, Baxter, Louise C., Shaw, Lynn C., Caballero, Sergio, Sengupta, Nilanjana, Calzi, Sergio Li, Sullivan, Sean M., Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965558/
https://ncbi.nlm.nih.gov/pubmed/17567755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702072104
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