IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth

Vessel loss precipitates many diseases. In particular, vessel loss resulting in hypoxia induces retinal neovascularization in diabetic retinopathy and in retinopathy of prematurity (ROP), major causes of blindness. Here we define insulin-like growth factor binding protein-3 (IGFBP3) as a new modulat...

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Detalhes bibliográficos
Main Authors: Lofqvist, Chatarina, Chen, Jing, Connor, Kip M., Smith, Alexandra C. H., Aderman, Christopher M., Liu, Nan, Pintar, John E., Ludwig, Thomas, Hellstrom, Ann, Smith, Lois E. H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965557/
https://ncbi.nlm.nih.gov/pubmed/17567756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702031104
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