Reversine increases the plasticity of lineage-committed mammalian cells

Previously, a small molecule, reversine, was identified that reverses lineage-committed murine myoblasts to a more primitive multipotent state. Here, we show that reversine can increase the plasticity of C2C12 myoblasts at the single-cell level and that reversine-treated cells gain the ability to di...

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Detalhes bibliográficos
Main Authors: Chen, Shuibing, Takanashi, Shinichi, Zhang, Qisheng, Xiong, Wen, Zhu, Shoutian, Peters, Eric C., Ding, Sheng, Schultz, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965539/
https://ncbi.nlm.nih.gov/pubmed/17566101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704360104
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