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Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability

BACKGROUND: Pain of mild to moderate grade is difficult to detect in laboratory mice because mice are prey animals that attempt to elude predators or man by hiding signs of weakness, injury or pain. In this study, we investigated the use of telemetry to identify indicators of mild-to-moderate post-l...

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Библиографические подробности
Главные авторы: Arras, Margarete, Rettich, Andreas, Cinelli, Paolo, Kasermann, Hans P, Burki, Kurt
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965463/
https://ncbi.nlm.nih.gov/pubmed/17683523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-3-16
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