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Seeking an ancient enzyme in Methanococcus jannaschii using orf, a program based on predicted secondary structure comparisons

We have developed a simple procedure to identify protein homologs in genomic databases. The program, called orf, is based on comparisons of predicted secondary structure. Protein structure is far better conserved than amino acid sequence, and structure-based methods have been effective in exploiting...

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Autors principals: Aurora, Rajeev, Rose, George D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19652/
https://ncbi.nlm.nih.gov/pubmed/9501173
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