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T cell activation requires mitochondrial translocation to the immunological synapse

T helper (T(h)) cell activation is required for the adaptive immune response. Formation of the immunological synapse (IS) between T(h) cells and antigen-presenting cells is essential for T(h) cell activation. IS formation induces the polarization and redistribution of many signaling molecules; howev...

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Detalhes bibliográficos
Main Authors: Quintana, Ariel, Schwindling, Christian, Wenning, Anna S., Becherer, Ute, Rettig, Jens, Schwarz, Eva C., Hoth, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964825/
https://ncbi.nlm.nih.gov/pubmed/17726106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703126104
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