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Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation
BACKGROUND: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main ORF by interfering with translational reinitiation at the main start codon. uORFs also occur by chance in the genome, in...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1964767/ https://ncbi.nlm.nih.gov/pubmed/17686169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-295 |
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