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Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation

BACKGROUND: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main ORF by interfering with translational reinitiation at the main start codon. uORFs also occur by chance in the genome, in...

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Detalhes bibliográficos
Main Authors: Cvijović, Marija, Dalevi, Daniel, Bilsland, Elizabeth, Kemp, Graham JL, Sunnerhagen, Per
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964767/
https://ncbi.nlm.nih.gov/pubmed/17686169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-295
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