Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1- and SIR-dependent transcriptional silencing

Candida glabrata is an important opportunistic pathogen causing both mucosal and bloodstream infections. C. glabrata is able to adhere avidly to mammalian cells, an interaction that depends on the Epa1p lectin. EPA1 is shown here to be a member of a larger family of highly related genes encoded in s...

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Bibliographic Details
Main Authors: De Las Peñas, Alejandro, Pan, Shih-Jung, Castaño, Irene, Alder, Jonathan, Cregg, Robert, Cormack, Brendan P.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC196462/
https://ncbi.nlm.nih.gov/pubmed/12952896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1121003
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