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Skewing X chromosome choice by modulating sense transcription across the Xist locus

The X-inactive-specific transcript (Xist) locus is a cis-acting switch that regulates X chromosome inactivation in mammals. Over recent years an important goal has been to understand how Xist is regulated at the initiation of X inactivation. Here we report the analysis of a series of targeted mutati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nesterova, Tatyana B., Johnston, Colette M., Appanah, Ruth, Newall, Alistair E.T., Godwin, Jonathan, Alexiou, Maria, Brockdorff, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196458/
https://ncbi.nlm.nih.gov/pubmed/12952890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271203
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