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Discovery of Genes Activated by the Mitochondrial Unfolded Protein Response (mtUPR) and Cognate Promoter Elements

In an accompanying paper, we show that the mitochondrial Unfolded Protein Response or mtUPR is initiated by the activation of transcription of chop through an AP-1 element in the chop promoter. Further, we show that the c/ebpβ gene is similarly activated and CHOP and C/EBPβ subsequently hetero-dimer...

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Autors principals: Aldridge, Jonathan E., Horibe, Tomohisa, Hoogenraad, Nicholas J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1964532/
https://ncbi.nlm.nih.gov/pubmed/17849004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000874
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