Identification of a DNA-binding site and transcriptional target for the EWS–WT1(+KTS) oncoprotein

Desmoplastic small round cell tumor (DSRCT) is defined by a chimeric transcription factor, resulting from fusion of the N-terminal domain of the Ewing's sarcoma gene EWS to the three C-terminal zinc fingers of the Wilms' tumor suppressor WT1. Although DNA-binding sites have been defined fo...

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Main Authors: Reynolds, Paul A., Smolen, Gromoslaw A., Palmer, Rachel E., Sgroi, Dennis, Yajnik, Vijay, Gerald, William L., Haber, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC196452/
https://ncbi.nlm.nih.gov/pubmed/12923058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1110703
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